Efstathia Thymiakou


I am currently a postdoctoral fellow in the lab of Prof. Dimitris Kardassis (IMBB-FORTH) working on the role of the nuclear receptor HNF4α in lipid metabolism. My work so far, reveals new targets of HNF4α involved in High-density lipoproteins (HDL) metabolism and the development of steatosis and enriches our knowledge on HDL functionality in non-alcoholic fatty liver disease (NAFLD). During my first postdoc in the lab of Prof. Vasso Episkopou (Imperial College London) I investigated the role of a newly identified ubiquitin ligase, Arkadia2C, in motor axon growth. The work was published in PLosBiology in 2013, revealing an involvement of BMP-Smad signaling in motor axon advancement. During my PhD in the lab of Prof. Dimitris Kardassis (IMBB-FORTH), I studied the transcriptional regulation of ABCA1, a membrane transporter of cholesterol and phospholipids, which plays important role in reverse cholesterol transport and protection from atherosclerosis (Biochemistry. 2007 Oct 16;46(41):11473-83, Biochim Biophys Acta. 2014 Jun;1839(6):526-36). I am a member of the European and Hellenic Atherosclerosis Society and of the Hellenic Society for Biochemistry and Molecular Biology and have presented my work in many national and international conferences.

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